We work and thrive in innovation hubs in the U.S. and Australia
Our founders had an early ambition to make Protagonist a global company, attracting the best and brightest from every region to its offices in Silicon Valley and Brisbane.

Bay Area - Newark, California
Our presence in the Bay Area launched with a small office in Redwood City in 2009, hosting the handful of employees who built the company’s U.S. presence—our CEO, Dinesh Patel, among them. Today, Protagonist is proudly headquartered at the Pacific Research Center in Newark, California, home to some of the region’s most vibrant biotechnology companies. Over decades, members of Protagonist’s management team have played important roles in the growth of biotech in the region. Their pioneering spirit carries through to our own company’s growth, attributable in part to the extraordinary innovation ecosystem that surrounds us in California.
The region’s future remains bright, consistently ranking within the top-tier of the world’s biotechnology clusters. Explore open positions in our Newark, California headquarters here.
Corporate Headquarters Protagonist Therapeutics Inc.
7707 Gateway Boulevard, Suite 140
Newark, CA 94560-1160
USA
Brisbane, Australia
Protagonist’s discovery platform was first conceived in the world-class research labs of the University of Queensland (UQ)—a fixture of Brisbane’s dynamic and growing life sciences community. There, our scientific founder, Mark Smythe, PhD, applied a deep understanding of combinatorial chemistry and molecular design to the development of tools for the discovery of novel drug compounds. Today, our Brisbane office has become a fixture, in its own right, of the area’s rich innovation ecosystem.
The advantages of our Brisbane office go well beyond the 280 days of sunshine enjoyed there per year. Today, our R&D scientists in Brisbane work hand-in-glove with our U.S. team to keep projects moving forward around the clock. A sought-after destination, Brisbane attracts top talent from across Australia, southeast Asia, and beyond.
Protagonist Pty Ltd
306 Carmody Road
St Lucia, Brisbane Qld 4072
AUSTRALIA

Join Our Team
We are motivated to make a difference for all those who can someday benefit from the therapies we discover and develop. Protagonist bring together leaders in the life sciences who share this sense of purpose. We invite you to connect with us and explore opportunities to participate in this great work.